{"id":344,"date":"2019-01-26T05:06:29","date_gmt":"2019-01-26T05:06:29","guid":{"rendered":"https:\/\/schultzwebdesign.se\/GL\/?page_id=344"},"modified":"2019-01-26T05:18:48","modified_gmt":"2019-01-26T05:18:48","slug":"history-of-discovery","status":"publish","type":"page","link":"https:\/\/schultzwebdesign.se\/GL\/paul-c-lauterbur-ph-d\/history-of-discovery\/","title":{"rendered":"History of Discovery"},"content":{"rendered":"<h1>Paul C. Lauterbur Ph.D.<\/h1>\n<p><b>The Nobel Prize in Physiology or Medicine 2003<\/b><br \/>\nNobel Co-recipient Sir Peter Mansfield<br \/>\n<b>The President&#8217;s<a href=\"http:\/\/www.nsf.gov\/od\/nms\/recip_details.jsp?recip_id=207\" target=\"_blank\" rel=\"noopener\"> National Medal of Science<\/a> &#8211; Physical Sciences 1987<br \/>\nThe National Medal of Technology and Innovation 1988<\/b><\/p>\n<p class=\"profilebk\">Chemist. Magnetic resonance imaging.<\/p>\n<p><em>&#8220;Every great idea in history has the red stamp of rejection on its face. If you scratch any innovation&#8217;s surface, you&#8217;ll find the scars: they&#8217;ve been roughed up and thrashed around by the masses and the leading minds before they made it into your life.&#8221;<\/em><\/p>\n<p class=\"heading center\">History or Discovery<\/p>\n<p><a href=\"http:\/\/magnetic-resonance.org\/ch\/20-01.html\" target=\"_blank\" rel=\"noopener\"><img class=\"logo_left\" src=\"http:\/\/www.gangalib.org\/images\/magres_title.png\" \/>An Excursion into the History of Magnetic Resonance Imaging.<\/a> <em>At bottom of page please click on successive page numbers.<\/em><\/p>\n<p><a href=\"http:\/\/www.nature.com\/physics\/looking-back\/lauterbur\/index.html\" target=\"_blank\" rel=\"noopener\"><img class=\"logo_left\" src=\"http:\/\/www.gangalib.org\/images\/nature_pub.jpg\" \/><\/a><\/p>\n<p><a href=\"http:\/\/www.nature.com\/physics\/looking-back\/lauterbur\/index.html\" target=\"_blank\" rel=\"noopener\">\u00a9 Nature Publishing Group 2006 <\/a><\/p>\n<p class=\"clear\"><a href=\"http:\/\/www.nature.com\/physics\/looking-back\/lauterbur\/index.html\" target=\"_blank\" rel=\"noopener\">Image Formation by Induced Local Interactions:<\/a> Examples Employing Nuclear Magnetic Resonance. Nature 242, 190-191 (1973).<\/p>\n<p>MRI &#8211; a new way of seeing<\/p>\n<p>In 1973, Paul Lauterbur described an imaging technique that removed the usual resolution limits due to the wavelength of the imaging field. He used two fields: one interacting with the object under investigation, the other restricting this interaction to a small region. Rotation of the fields relative to the object produces a series of one-dimensional projections of the interacting regions, from which two- or three-dimensional images of their spatial distribution can be reconstructed. Application of this technique as magnetic resonance imaging is now widespread.<\/p>\n<div class=\"bookimg\"><img src=\"http:\/\/www.gangalib.org\/images\/mit_press.jpg\" width=\"100\" \/><\/div>\n<div class=\"bookinfo\">\n<div class=\"leftcol\">Title<\/div>\n<div class=\"rightcol\">Paul Lauterbur and the Invention of MRI<\/div>\n<div class=\"leftcol\">Author:<\/div>\n<div class=\"rightcol\"><b>M. Joan Dawson<\/b><\/div>\n<div class=\"leftcol\">Publisher<\/div>\n<div class=\"rightcol\">MIT Press, 2013<\/div>\n<div class=\"leftcol\">ISBN:<\/div>\n<div class=\"rightcol\">0262316722, 9780262316729<\/div>\n<div class=\"leftcol\">Length:<\/div>\n<div class=\"rightcol\">296 pages<\/div>\n<div class=\"leftcol\">Subjects:<\/div>\n<div class=\"rightcol\">Medical, Diagnostic Imaging, General<\/div>\n<\/div>\n<p>About the Author: <b>M. Joan Dawson<\/b> is Associate Professor Emerita in the School of Molecular and Cellular Biology at the University of Illinois at Urbana-Champaign. She was married to Paul Lauterbur from 1984 until his death in 2007.<\/p>\n<p class=\"heading\">Overview<\/p>\n<p>On September 2, 1971, the chemist Paul Lauterbur had an idea that would change the practice of medical research. Considering recent research findings about the use of nuclear magnetic resonance (NMR) signals to detect tumors in tissue samples, Lauterbur realized that the information from NMR signals could be recovered in the form of images-and thus obtained noninvasively from a living subject. It was an unexpected epiphany: he was eating a hamburger at the time. Lauterbur rushed out to buy a notebook in which to work out his idea; he completed his notes a few days later. He had discovered the basic method used in all MRI scanners around the world, and for this discovery he would share the Nobel Prize for Physiology or Medicine in 2003. This book, by Lauterbur&#8217;s wife and scientific partner, M. Joan Dawson, is the story of Paul Lauterbur&#8217;s discovery and the subsequent development of the most important medical diagnostic tool since the X-ray.<\/p>\n<p>With MRI, Lauterbur had discovered an entirely new principle of imaging. Dawson explains the science behind the discovery and describes Lauterbur&#8217;s development of the idea, his steadfastness in the face of widespread skepticism and criticism, and related work by other scientists including Peter Mansfield (Lauterbur&#8217;s Nobel co-recipient), and Raymond Damadian (who famously feuded with Lauterbur over credit for the ideas behind MRI). She offers not only the story of one man&#8217;s passion for his work but also a case study of how science is actually done: a flash of insight followed by years of painstaking work.<\/p>\n<p class=\"heading\">About the Author<\/p>\n<p>M. Joan Dawson is Associate Professor Emerita in the School of Molecular and Cellular Biology at the University of Illinois at Urbana-Champaign. She was married to Paul Lauterbur from 1984 until his death in 2007. &#8220;Life is so strange. It was because of the tortured history of NMR Specialties that Paul happened to be on hand to witness the experiments that raised in his mind the possibility of Magnetic Resonance Imaging. Paul was always squeamish about everything medical and biological, everything that had to do with blood and other tissues. He was loath to go to doctors and totally intimidated by the idea that he might have to have an injection or to have blood drawn. So finding a way to do NMR studies noninvasively took on a special meaning for him.&#8221;<\/p>\n<p class=\"heading\">Reviews<\/p>\n<p>&#8220;The book reads well and has something for everyone; I would particularly recommend it to young researchers.&#8221;-Chemistry World<\/p>\n<p class=\"heading\">Endorsements<\/p>\n<p><em>&#8220;Paul Lauterbur and the Invention of MRI<\/em> is a fascinating story, told by the loving wife of a major contributor. Science reports are seldom just right or wrong but live from personal impressions that bring colors into the picture. This account of a major advancement in medicine offers a rare glimpse into the inner workings of science progress.&#8221;-<b>Richard R. Ernst<\/b>, ETH, Z\u00fcrich, Switzerland; 1991 Nobel Laureate in Chemistry<\/p>\n<p><a href=\"http:\/\/www.the-scientist.com\/?articles.view\/articleNo\/37299\/title\/Book-Excerpt-from-Paul-Lauterbur-and-the-Invention-of-MRI\/\" target=\"_blank\" rel=\"noopener\">Book Excerpt<\/a>. In Chapter 6, &#8220;The first fruitful weeks,&#8221; author M. Joan Dawson describes her late husband&#8217;s first steps in the invention of a revolutionary imaging technology.<\/p>\n<div class=\"bookimg\"><img src=\"http:\/\/www.gangalib.org\/images\/pioneersofmri.png\" width=\"100\" \/><\/div>\n<div class=\"bookinfo\">\n<div class=\"leftcol\">Title<\/div>\n<div class=\"rightcol\"><b>The pioneers of NMR and magnetic resonance in medicine: the story of MRI <\/b><\/div>\n<div class=\"leftcol\">Author:<\/div>\n<div class=\"rightcol\">James Mattson, Merrill Simon<\/div>\n<div class=\"leftcol\">Edition:<\/div>\n<div class=\"rightcol\">Illustrated<\/div>\n<div class=\"leftcol\">Publisher:<\/div>\n<div class=\"rightcol\">Bar-Ilan University Press<\/div>\n<div class=\"leftcol\">ISBN:<\/div>\n<div class=\"rightcol\">0961924314, 9780961924317<\/div>\n<div class=\"leftcol\">Subjects:<\/div>\n<div class=\"rightcol\">Medical, Diagnostic Imaging<\/div>\n<\/div>\n<div class=\"bookimg\"><img src=\"http:\/\/www.gangalib.org\/images\/no_cover_thumb.gif\" width=\"100\" \/><\/div>\n<div class=\"bookinfo\">\n<div class=\"leftcol\">Title<\/div>\n<div class=\"rightcol\"><b>Paul C. Lauterbur Notebook Genesis of MRI, 1971<\/b><\/div>\n<div class=\"leftcol\">Author:<\/div>\n<div class=\"rightcol\">Paul C.Lauterbur<\/div>\n<div class=\"leftcol\">Edition\/<br \/>\nFormat:<\/div>\n<div class=\"rightcol\">Manuscript Archival Material: English<\/div>\n<div class=\"leftcol\">Summary:<\/div>\n<div class=\"rightcol\">This is six pages of writing in a research notebook kept by Paul C. Lauterbur (positives and carbon copies) dated September 2, 3, 1971 and September 6, September 7, 1971 in which Dr. Lauterbur sketches out a general concept and considers practical applications for the concept of MRI (magnetic resonance imaging).<\/div>\n<div class=\"leftcol\">Description:<\/div>\n<div class=\"rightcol\">1 box (1 notebook)<br \/>\nAvailable in Chemical Heritage Foundation, Othmer Library of Chemical History, Philadelphia, PA 19106 USA.<\/div>\n<\/div>\n<div class=\"bookimg\"><img src=\"http:\/\/www.gangalib.org\/images\/no_cover_thumb.gif\" width=\"100\" \/><\/div>\n<div class=\"bookinfo\">\n<div class=\"leftcol\">Title<\/div>\n<div class=\"rightcol\">From Thales to Lauterbur, Or from the Lodestone to MR Imaging: Magnetism and Medicine<\/div>\n<div class=\"leftcol\">Edition:<\/div>\n<div class=\"rightcol\">Reprint<\/div>\n<div class=\"leftcol\">Published:<\/div>\n<div class=\"rightcol\">1991<\/div>\n<div class=\"leftcol\">Length:<\/div>\n<div class=\"rightcol\">20 pages<\/div>\n<\/div>\n<div class=\"bookimg clear\"><img src=\"http:\/\/www.gangalib.org\/images\/logo_wcmasthead_en.png\" alt=\"World Cat\" \/><\/div>\n<p class=\"clear\">Paul C. Lauterbur. <a href=\"https:\/\/www.worldcat.org\/search?q=kw%3APaul+C.+Lauterbur+&amp;qt=advanced&amp;dblist=638\" target=\"_blank\" rel=\"noopener\"> Find in a library near you.<\/a> In Worldcat page, click book of interest to you. Scroll down to libraries which possess book. Possibly more than one person with same name<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Paul C. Lauterbur Ph.D. The Nobel Prize in Physiology or Medicine 2003 Nobel Co-recipient Sir Peter Mansfield The President&#8217;s National Medal of Science &#8211; Physical Sciences 1987 The National Medal of Technology and Innovation 1988 Chemist. Magnetic resonance imaging. &#8220;Every great idea in history has the red stamp of rejection on its face. If you [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":336,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/schultzwebdesign.se\/GL\/wp-json\/wp\/v2\/pages\/344"}],"collection":[{"href":"https:\/\/schultzwebdesign.se\/GL\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/schultzwebdesign.se\/GL\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/schultzwebdesign.se\/GL\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/schultzwebdesign.se\/GL\/wp-json\/wp\/v2\/comments?post=344"}],"version-history":[{"count":1,"href":"https:\/\/schultzwebdesign.se\/GL\/wp-json\/wp\/v2\/pages\/344\/revisions"}],"predecessor-version":[{"id":345,"href":"https:\/\/schultzwebdesign.se\/GL\/wp-json\/wp\/v2\/pages\/344\/revisions\/345"}],"up":[{"embeddable":true,"href":"https:\/\/schultzwebdesign.se\/GL\/wp-json\/wp\/v2\/pages\/336"}],"wp:attachment":[{"href":"https:\/\/schultzwebdesign.se\/GL\/wp-json\/wp\/v2\/media?parent=344"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}